In 1877, on St. Thomas' Day at Westminster Abbey, London, Rev Thomas Valpy French was appointed the first Anglican Bishop of Lahore, a large diocese which included all of the Punjab, then under British colonial rule, and remained so until 1887; during this period he also opened the Divinity College, Lahore in 1870. Rev Thomas Patrick Hughes served as a Church Missionary Society missionary at Peshawar (1864–84), and became an oriental scholar, and compiled a 'Dictionary of Islam' (1885).Sacred Heart Cathedral, Lahore Missionaries accompanied colonizing forces from Portugal, France, and Great Britain. Jesuit missionaries sent from their Portuguese-held Goa built a Catholic church in Lahore, the first in Punjab, around 1597, two years after being granted permission by emperor Akbar, who had called them to his court in Fatehpur Sikri for religious discussions. This church was later demolished, perhaps during Aurangzeb times. Later on, Christianity was mainly brought by the British rulers of India in the later 18th and 19th century. This is evidenced in cities established by the British, such as the port city of Karachi, where the majestic St. Patrick's Cathedral, one of Pakistan's largest church, stands, and the churches in the city of Rawalpindi, where the British established a major military cantonment.

The Europeans won small numbers of converts to Anglicanism, Methodism, the Lutheran Church and Catholicism from the native populations. Islam was very strong in the provinces of Punjab, Balochistan and the North West Frontier Province, but small native communities of converts to Christianity were formed. The largest numbers came from resident officers of the British Army and the government. European and wealthy native Christians established colleges, churches, hospitals and schools in cities like Karachi, Lahore, Rawalpindi and Peshawar. There is a large Catholic Goan community in Karachi which was established when Karachi's infrastructure was developed by the British before World War II, and the Irish (who were subjects of the British Empire and formed a large part of the British Army) were an important factor in the establishment of Pakistan's Catholic community.

Protestantism is the second largest form of Christianity with collectively more than 900 million adherents worldwide or nearly 40% of all Christians.It originated with the Reformation, a movement against what its followers considered to be errors in the Roman Catholic Church. Ever since, Protestants reject the Roman Catholic doctrine of papal supremacy and sacraments, but disagree among themselves regarding the real presence of Christ in the Eucharist. They emphasize the priesthood of all believers, justification by faith alone (sola fide) rather than by good works, and the highest authority of the Bible alone (rather than with sacred tradition) in faith and morals (sola scriptura). The "Five solae" summarize basic theological differences in opposition to the Roman Catholic Church.Protestantism is popularly considered to have begun in Germany in 1517 when Martin Luther published his Ninety-five Theses as a reaction against abuses in the sale of indulgences by the Roman Catholic Church, which purported to offer remission of sin to their purchasers. However, the term derives from the letter of protestation from German Lutheran princes in 1529 against an edict of the Diet of Speyer condemning the teachings of Martin Luther as heretical. Although there were earlier breaks and attempts to reform of the Roman Catholic Church — notably by Peter Waldo, John Wycliffe, and Jan Hus — only Luther succeeded in sparking a wider, lasting, and modern movement. In the 16th century, Lutheranism spread from Germany into Denmark, Norway, Sweden, Finland, Latvia, Estonia, and Iceland. Reformed (or Calvinist) denominations spread in Germany, Hungary, the Netherlands, Scotland, Switzerland and France by reformers such as John Calvin, Huldrych Zwingli, and John Knox. The political separation of the Church of England from the pope under King Henry VIII began Anglicanism, bringing England and Wales into this broad Reformation movement

When Pakistan achieved independence in 1947, the organization and activities of the Christian community changed drastically. Christians in Punjab and Sindh had been quite active after 1945 in their support for Muhammad Ali Jinnah's Muslim League. Even before the final phase of the movement, leading Indian Christians like Pothan Joseph had rendered valuable services as journalists and propagandists of the Muslim League. Jinnah had repeatedly promised all citizens of Pakistan complete equality of citizenship, but this promise was not kept by his successors. Pakistan became an Islamic Republic in 1956, making Islam the source of legislation and cornerstone of the national identity, while guaranteeing freedom of religion and equal citizenship to all citizens. In the mass population exchanges that occurred between Pakistan and India upon independence due to conflict between Muslims and followers of Indian religions, most Hindus and nearly all Sikhs fled the country. Pakistani Punjab is now over 2% Christian, with very few Hindus left. Christians have made some contributions to the Pakistani national life. Pakistan's first non-Muslim Chief Justice of Pakistan Supreme Court was Justice A. R. Cornelius. Pakistani Christians also distinguished themselves as great fighter pilots in the Pakistan Air Force. Notable amongst them are Cecil Chaudhry, Peter O'Reilly and Mervyn L Middlecoat. Christians have also contributed as educationists, doctors, lawyers and businessmen. One of Pakistan's cricketers, Yousuf Youhana, was born Christian, but later on converted to Islam, taking the Islamic name Mohammad Yousuf. In Britain, the bishop emeritus of Rochester Michael Nazir-Ali is a Pakistani Christian.

There is no definitive figure, but Christians make up roughly 1.6% of the population of Pakistan, as many as Hindus, according to the latest official statistics.Christians mostly converted from Hinduism to escape the caste-dominated Indian society before the partition of India and Pakistan in 1947. But changing religion didn’t help: the roots of discrimination based on caste run deep in both Indian and Pakistani society.The plight of Christians has persisted for decades, but there has also been a rise of hatred against Christians since the late 1980s, when the dictator Zia ul Haq introduced Pakistan’s blasphemy law, particularly used to persecute Christians.

But even among minorities, Christians are particularly singled out, for a number of reasons. They are visible: they live mostly in urban areas and are often employed in low-wage jobs. They are also the poorest of the community. In December 2015, the Capital Development Authority of Islamabad submitted a report suggesting that the Christian “ugly slums” of the capital be destroyed to keep the city clean. The CDA, in this unprecedentedly stupid move (“their Trump Moment” as the English daily Dawn put it), argued that the campaign of destruction would preserve Islamabad’s aesthetics and maintain its Muslim-majority demographic balance.The proposal was rightly contested by political parties, activists, and NGOs and thwarted by the Supreme Court, but it was a worrying sign of just how poorly Christians are thought of by the Pakistani elite.Christians are historically considered to have positively contributed to Pakistani statehood, thus helping the development of the Pakistani society, but today they, along with other non-Muslims, are forbidden from holding high office. The Christian vote in Pakistan is around 1.3 million, second to the Hindu vote, which is around 1.5 million. While the Hindu vote is mostly concentrated in the Sindh and Punjab regions, Christian voters are more scattered. Since the minority vote is restricted to a few electorates, political parties are not generally interested in serving them, though there is a lot of lip service to minority issues.Minority representatives protest the problem of segregation from mainstream politics. There is no doubt that the electoral system adds to the problems of already frustrated minority communities in Pakistan. Minorities don’t have the right to place their own candidates in elections. They can vote for any Muslim candidate in their constituency from within the general seats, and they also have the right to vote for a minority candidate, but they don’t have the right to choose these. They are instead given minority seats for which tickets are allotted by mainstream political parties.